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This study demonstrates that inhibition of inflammasome pathway protects against hyperoxia-induced lung and brain injury in newborn rats. Targeting this pathway may provide novel therapy for lung and brain injury in preterm infants.
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This page is a summary of: Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice, American Journal of Respiratory Cell and Molecular Biology, September 2019, American Thoracic Society,
DOI: 10.1165/rcmb.2018-0192oc.
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