Microbiota Contribute to Obesity-related Increases in the Pulmonary Response to Ozone

What is it about?

Obesity is a risk factor for asthma, especially non-atopic asthma. We now show that the microbiome contributes to the exaggerated responses to the non-atopic asthma trigger, ozone, that are observed in obese mice. Our data showing beneficial effects of the dietary fiber, pectin, on responses to ozone suggest that microbiota-based therapies such as probiotics and prebiotics, may ultimately prove useful in the treatment of obese asthmatic patients.

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