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IPF fibroblasts are apoptosis resistant. Our studies demonstrated a novel mechanism that glutaminolysis epigenetically up-regulates anti-apoptotic genes XIAP and survivin in IPF fibroblasts.

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This page is a summary of: Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts, American Journal of Respiratory Cell and Molecular Biology, January 2019, American Thoracic Society,
DOI: 10.1165/rcmb.2018-0180oc.
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