Solid State Characterization of Withania somnifera (Ashwagandha) Root Extract

What is it about?

The aim of the current study was to evaluate the influence of Consciousness Energy Healing Treatment (The Trivedi Effect®) on the physico-chemical, thermal and behavioral properties of ashwagandha root extract using powder X-ray diffraction (PXRD), particle size distribution analysis (PSD), Fourier transform infrared (FT-IR) spectrometry, UV-Vis spectroscopy, thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC).

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Why is it important?

The current study revealed that Consciousness Energy Healing Treatment (The Trivedi Effect®) has the significant effect on the surface area, particle size, and thermal stability of the ashwagandha root extract. The PXRD analysis concluded that both the control and treated samples were amorphous in nature. The particle size values at d10, d50, and d90 of the treated sample were significantly decreased by 36.78%, 15.18%, and 5.06%, respectively compared with the control sample. Likewise, the surface area of the treated sample was significantly increased by 85.14% compared to the control sample. FT-IR results showed a small impact of Consciousness Energy Healing Treatment on the phytoconstituents of ashwagandha root extract at the atomic level to reduce the force constant of O-H (str.) bond. UV-vis analysis revealed that the wavelength for the maximum absorbance (λmax) of both the samples was at 206.4. TGA data revealed three steps of thermal degradation and the total weight loss was decreased by 0.73% in the treated sample compared to the control sample. Consequently, the maximum thermal degradation temperature at 272.53°C and 393.35°C for two broad peaks in the treated sample was increased by 0.05% and 0.08%, respectively compared to the control the sample (272.67°C and 393.66°C). The DSC analysis indicated that the evaporation temperature and latent heat of vaporization were significantly decreased by 4.98% and 35.67%, respectively in the treated sample compared with the control sample. In summary, Energy of Consciousness Healing Treated ashwagandha root extract could have better solubility, absorption, dissolution, bioavailability, and longterm storage stability compared with the control sample and could be suitable for any pharmaceutical and nutraceutical formulation which might be providing better therapeutic response against various diseases such as allergies and septic shock, diabetes mellitus, stress-related disorders like anxiety, insomnia, depression, sleep disorder, mental restlessness (mind chattering), brain frog, impotency, lack of motivation, low libido, mood swings, confusion, migraines, headaches, forgetfulness, overwhelm, fear of the future, indecisiveness, worthlessness, frustration, irritability, loneliness, obsessive/compulsive behavior, chronic fatigue, and panic attacks; immunological and inflammatory diseases disorders like Hashimoto Thyroiditis, Diabetes, Lupus, Systemic Lupus Erythematosus, Chronic peptic ulcers, Asthma, Chronic active hepatitis, Tuberculosis, Hepatitis, Addison Disease, Graves’ Disease, Pernicious, Crohn’s disease, Rheumatoid arthritis, Irritable Bowel Syndrome, Aplastic Anemia, Multiple Sclerosis, Chronic periodontitis, Ulcerative colitis, Chronic sinusitis, Atherosclerosis, Myasthenia Gravis, Diverticulitis, Dermatitis, Arthritis, Psoriasis, Alopecia Areata, Scleroderma, Chronic Fatigue Syndromeaging-related diseases like cardiovascular disease, arthritis, cancer, dementia, cataracts, Alzheimer’s disease, osteoporosis, diabetes, glaucoma, hearing loss, hypertension, Parkinson’s Disease, Motor Neurone Disease, Prion Disease, Spinocerebellar Ataxia, Friedreich’s Ataxia, Spinal muscular atrophy, Lewy Body Disease, chronic infections, and many more.