Characterization of Physical, Thermal and Spectral Properties of Biofield Treated 2,6-Dichlorophenol

What is it about?

2,6-Dichlorophenol (2,6-DCP) is a compound used for the synthesis of chemicals and pharmaceutical agents. The present work is intended to evaluate the impact of Mr. Trivedi’s biofield energy treatment on physical, thermal and spectral properties of the 2,6-DCP. The control and treated 2,6-DCP were characterized by various analytical techniques such as X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR) spectroscopy, and ultra violet-visible spectroscopy (UV-vis) analysis. The XRD results showed the increase in crystallite size of treated sample by 28.94% as compared to the control sample. However, the intensity of the XRD peaks of treated 2,6-DCP were diminished as compared to the control sample. The DTA analysis showed a slight increase in melting temperature of the treated sample. Although, the latent heat of fusion of the treated 2,6-DCP was changed substantially by 28% with respect to the control sample. The maximum thermal decomposition temperature (Tmax) of the treated 2,6-DCP was decreased slightly in comparison with the control. The FT-IR analysis showed a shift in C=C stretching peak from 1464→1473 cm-1 in the treated sample as compared to the control sample. However, the UV-vis analysis showed no changes in absorption peaks of treated 2,6-DCP with respect to the control sample. Overall, the result showed a significant effect of biofield energy treatment on the physical, thermal and spectral properties of 2,6-DCP. It is assumed that increase in crystallite size and melting temperature of the biofield energy treated 2,6-DCP could alleviate its reaction rate that might be a good prospect for the synthesis of pharmaceutical compounds.

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Why is it important?

Phenol derivatives are commonly used in the pharmaceuticals, wood preservatives, rubber chemicals, dyes, pigments, explosives and industrial solvents [1]. Chlorophenols are known as the organochlorides of phenol that contains one or more covalently bonded chlorine atoms. These compounds are produced by the electrophilic halogenation of phenol with chlorine. Chlorophenols are commonly used as pesticides, herbicides, and disinfectants [2]. 2,4-Dichlorophenol was used as an intermediate for the synthesis of Bithionol, which is an anthelmintic drug of choice for treating human infected with Fasciola hepatica. It is used as an alternative drug for treating pulmonary and cerebral paragonimiasis [3]. 2,6-Dichlorophenol (2,6-DCP) is a compound used as a sex pheromone of the tropical horse tick Anocentor nitens belongs to Ixodidae family [4]. Additionally, an 2,6-DCP indophenol is use as a redox dye which can be used to measure the rate of photosynthesis [5]. Cabello et al. reported that 2,6-DCP indophenol may serve as pro-oxidant chemotherapeutic targeting human cancer cells in an animal model of human melanoma. This compound induces cancer cell death by depleting the intracellular glutathione and upregulation of oxidative stress [6]. 2,6-DCP is also used for synthesis of pharmaceutical intermediate compounds [7]. Pharmaceutical stability is an important factor that governs the therapeutic efficacy and toxicity of the medications. Based on Food and Drug Administration (FDA) regulations, the drug companies should determine a time limit to which they can assure the full potency and stability of the medications [8]. Thus, efficacious drugs with adequate shelf life are essential for their successful medical applications. Moreover, the chemical and physical stability of the pharmaceutical compounds are more desired quality attributes that directly affect its safety, efficacy, and shelf life [9]. Hence, some alternate approach should be used to improve the physicochemical properties of these compounds. Biofield energy was recently used as a method for modification of chemical, and thermal properties of various metals [10], organic compound [11], organic product [12], and pharmaceutical drugs [13]. Therefore, authors have planned to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of 2,6-DCP. The National Centre for Complementary and Alternative Medicine (NCCAM), which is an integral part of the prestigious National Institute of Health (NIH), allows the use of Complementary and Alternative Medicine (CAM) therapies as an alternative in the healthcare field. About 36% of US citizens regularly use some form of CAM [14], in their daily activities. CAM embraces numerous energy-healing therapies; biofield therapy is one of the energy medicines used worldwide to alleviate overall human health. Biofield therapy is known as a treatment modality that confers a change in people’s health and well-being by interacting with their biofield [15]. The most commonly used biofield therapies are Reiki, therapeutic touch and Qi gong that are performed by the experts. Biofield energy healing is a healing therapy that works on the quantum level, and addresses physical, mental, emotional and spiritual imbalances simultaneously [15]. Moreover, the health of a human being also depends on the balance of the bioenergetics fields. It is believed that during the diseased condition this bioenergetics field is depleted [16]. Additionally, this biofield energy can be manipulated by the experts who are well versed in energy healing practice [17]. Therefore, it is suggested that human beings have the ability to harness the energy from the surrounding environment/Universe and can transmit into any object (living or non-living) around the Globe. The object(s) always receive the energy and responding in a useful manner that is called biofield energy. Mr. Trivedi is known to transform the characteristics in various research fields such as biotechnology [18], microbiology [19] and agriculture [20]. This biofield energy treatment is also known as The Trivedi Effect®. Hence, by capitalizing on the unique biofield energy treatment and pharmaceutical properties of 2,6-DCP, this research work was perused to investigate the impact of biofield energy treatment on the physical, thermal and spectral properties of this compound. The control and treated samples were analyzed using various analytical techniques such as X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR) spectroscopy, and ultra violet-visible spectroscopy (UV-vis) analysis.

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