Sleep and Pathological Wakefulness at the Time of Liberation from Mechanical Ventilation (SLEEWE). A Prospective Multicenter Physiological Study

What is it about?

Patients under mechanical ventilation who are not capable of sustaining spontaneous breathing despite the presence of general criteria are characterized by brain dysfunction. Specifically, there is a poor correlation between the activity of the two hemispheres in terms of sleep depth, and these patients never reach full awakening based on electrical activity. Pathological wakefulness seems to be a marker of difficult weaning from mechanical ventilation.

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