What is it about?

Hypoxemia is the most common complication of emergent endotracheal intubation. Provision of supplemental oxygen by nasal cannula during laryngoscopy (apneic oxygenation) has been shown in small randomized trials to prevent desaturation during elective intubation of healthy preoperative patients and has been recommended during intubation of the acutely ill, although it has never been tested in this setting. The FELLOW randomized trial found no difference between apneic oxygenation and usual care in the lowest oxygen saturation experienced by critically ill adults undergoing emergent endotracheal intubation.

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Why is it important?

The FELLOW Trial is the only randomized trial of apneic oxygenation during intubations outside of the operating room and is five times larger than any prior trial.

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This page is a summary of: Randomized Trial of Apneic Oxygenation during Endotracheal Intubation of the Critically Ill, American Review of Respiratory Disease, February 2016, American Thoracic Society,
DOI: 10.1164/rccm.201507-1294oc.
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