What is it about?
Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea
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Why is it important?
Obstructive sleep apnea is common in people with hypertension, particularly resistant hypertension. Treatment with an antihypertensive agent alone is often insufficient to control hypertension in patients with obstructive sleep apnea.
Perspectives
Losartan, 50 mg daily, reduces blood pressure in obstructive sleep apnea but with a smaller effect than it does in patients without sleep apnea. CPAP treatment in addition to Losartan may reduce blood pressure in a clinically relevant way in patients with new-onset hypertension and obstructive sleep apnea.
Prof. Dr Yuksel Peker
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This page is a summary of: Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea, American Review of Respiratory Disease, February 2016, American Thoracic Society,
DOI: 10.1164/rccm.201505-0998oc.
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