What is it about?
Smokers with low body mass, and those with immune cells reacting to self proteins could sustain a faster decline in lung function and emphysema in active smokers.
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Why is it important?
New immune-based biomarkers that accurately predict rapid loss of lung function in smokers, could provide new personalized therapy focused on removal of auto reactive cells.
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This page is a summary of: Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD), American Review of Respiratory Disease, November 2015, American Thoracic Society,
DOI: 10.1164/rccm.201504-0736oc.
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