Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells

Ivonne Torres-Atencio, Sara Rosero, Ciara Ordoñez, Michelle Ruiz, Amador Goodridge
  • American Journal of Respiratory and Critical Care Medicine, September 2018, American Thoracic Society
  • DOI: 10.1164/rccm.201803-0436le

What is it about?

Tuberculosis control relies on novel diagnosis methods and the development of an appropriate vaccine. By studying the immune response, we can elucidate new targets for laboratory test development. Our study demonstrates that Mycobacterium tuberculosis lipids are able to activate mast cells and thus offer a new gateway for disease diagnostics.

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http://dx.doi.org/10.1164/rccm.201803-0436le

The following have contributed to this page: Dr Amador Goodridge

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