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A multi-pronged approach was used to identify causal variants that are located in a genomic region nearby FAM13A gene that is frequently associated with one of the most prevalent pulmonary diseases: COPD. This helps to understand the biological foundation of human genetic association studies in COPD.
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This page is a summary of: Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays, American Review of Respiratory Disease, January 2019, American Thoracic Society,
DOI: 10.1164/rccm.201802-0337oc.
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