Longitudinal Modeling of Lung Function Trajectories in Smokers with and without Chronic Obstructive Pulmonary Disease

What is it about?

Individuals exposed to cigarette smoke have different rates of lung function decline over the course of their life. In this study, we used a quantitative method to identify four distinct groups of people who tend to respond to smoke exposure in similar ways. There appears to be a genetic basis for group membership, and patterns of lung abnormality also differ between groups.

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