Probiotic enhanced immunity and mental wellbeing of generally healthy women: a randomised, placebo-controlled and double-blind study

What is it about?

The result of WHQ data revealed that probiotics had a marked positive impact on mood and appetite, while also contributing to reductions in somatic complaints and enhancements in sleep quality. The probiotic intervention notably improved scores related to anxiety and sexual discomfort, further underscoring its broad benefit on women's well-being. On a molecular level, the probiotic group exhibited significant upregulation in genes associated with immune and mental health, including those related to anti-inflammatory responses and innate immune activity. This suggested that Probio87 enhanced immune defence mechanisms primarily through the modulation of NK cell functions and IL-10 production. The upregulation of genes linked to mental health, such as serotonin, GABA, BDNF and TPH-2, further supported the potential for probiotics to positively influence psychological well-being. This study underscores the potential of probiotics as a beneficial intervention for improving various facets of women's health, particularly through mental health enhancement, immune system modulation, and symptom relief.

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