Antifungal activity of Azadirachta indica (Neem), Tephrosia vogelii (Utupa) and Diospyros shimbaensis extracts against Aspergillus flavus and Aspergillus parasiticus

What is it about?

The present study focused on investigating the antifungal activity of the leaves of Azadirachta indica (Neem), Tephrosia vogelii (Utupa), and Diospyros shimbaensis against A. flavus and A. parasiticus. Leaf samples of A. indica, T. vogelii, and D. shimbaensis were extracted by Soxhlet and maceration methods, using methanol. Antiaflatoxigenic activities of the extracts of A. indica, T. vogelii, and D. shimbaensis were analysed by using high-performance liquid chromatography (HPLC) with a fluorescence detector. The leaf extracts of T. vogelii could control aflatoxin production in A. flavus by 97.8 ± 0.03% just as it reduced aflatoxin levels in A. parasiticus by 97.3 ± 0.22% at the lowest concentration of 125 µg/ml. Nevertheless, the leaf extracts of D. shimbaensis were found as the most effective at controlling both growth (by 40.74%) and aflatoxin production (by > 98%) against A. flavus at the lowest concentration of 125 µg/ml.

Featured Image