What is it about?
Increased heart rate (HR) is associated with cardiovascular and all-cause death. However, the result of epidemiological studies investigated the association between HR and stroke showed inconsistent results. We used 24-h measurement of HR and examined the association between HR and subclinical brain disease. Our result showed the increased HR is associated with a subclinical brain lesion.
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Why is it important?
Stroke kills 140 000 American each year. More than 795 000 people in the US have a stroke every year. Stoke is also a leading cause of serious long-term disability. Although subclinical brain lesions possess the risk for subsequent stroke, brain MRI for the purpose of screening is not cost-effective. Our finding is important because it suggests that individuals with high night-time HR are likely to have subclinical brain lesions. Our study provides the ground for the close follow-ups and aggressive treatment of individuals with high night-time HR as those interventions may be beneficial in preventing the future stroke.
Perspectives
Patients with heart failure are known to be high-risk of stroke. Interestingly, lower HR is associated more stroke in patients with HF. The contrary result of our study implies its underlining mechanism to stroke is different between patients with HF and the general population. I personally learn a lot particularly the basic mechanism of stroke through this project
Dr Tetz Cheng-Che Lee
Columbia University
Read the Original
This page is a summary of: Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly, Stroke, December 2017, Wolters Kluwer Health,
DOI: 10.1161/strokeaha.117.019355.
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