What is it about?

This is a review article that evaluates the association between atrial fibrillation and cognitive decline.

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Why is it important?

There is a focus on the association between silent stroke, cognitive decline, and atrial fibrillation, since oral anticoagulation may be a means of prevention of this mechanism.

Perspectives

Silent strokes are common in patients with atrial fibrillation, and many of these patients have low risk of a clinical stroke based on our current risk stratification tools. Clinical trials are needed to determine the effect of oral anticoagulation on cognitive decline in patients with atrial fibrillation, particularly patients at low risk of stroke who would otherwise not receive oral anticoagulation.

Dr Sean D Pokorney
Duke University Medical Center

Read the Original

This page is a summary of: Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke?, Journal of the American Heart Association, August 2015, Wolters Kluwer Health,
DOI: 10.1161/jaha.114.001573.
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