What is it about?

Our study demonstrated that physical activity both before and during pregnancy can prevent the develpment of preeclampsia, a pregnancy associated disease where there is an increase in blood pressure and protein in the urine. Indeed, it completely normalized fetal growth and placental development as well as prevented the increase in blood pressure during pregnancy. We also found a modulation of some components of a system which is implicated in the control of blood pressure which could be a potential novel therapeutic avenue for this disease.

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Why is it important?

This suggests that larger studies should be conducted to assess the effect of physical activity in women at increased risk of preeclampsia as exercise could be used as a preventive strategy for these women. Further studies need to be conducted to assess the potential therapeutic use of the components for which we have a modulation.

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This page is a summary of: Novel Role of the Renin-Angiotensin System in Preeclampsia Superimposed on Chronic Hypertension and the Effects of Exercise in a Mouse Model, Hypertension, October 2013, Wolters Kluwer Health,
DOI: 10.1161/hypertensionaha.113.01983.
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