What is it about?

The paper highlights the importance of ultrastructural examination using electron microscopy of glomeruli in kidney transplant biopsies to make a diagnosis of transplant glomerulopathy, a glomerular lesion in kidney transplants that is often a feature of chronic antibody-mediated graft rejection.

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Why is it important?

If electron microscopy of kidney transplant biopsies is not done routinely, early diagnosis of transplant glomerulopathy , and the potential to intervene in progressive graft failure, will be missed.

Perspectives

Hopefully this article changes the practice of kidney pathologists who are reporting kidney transplant biopsies.

Ian Gibson
University of Manitoba

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This page is a summary of: Transplant Glomerulopathy: Importance of Ultrastructural Examination, Glomerular Diseases, March 2021, Karger Publishers,
DOI: 10.1159/000513522.
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