What is it about?

Behçet's disease is mainly associated with HLA-B51 in Southern Tunisia. This antigen was not associated with recurrent aphthous stomatitis (RAOU) ; however, it had an impact on clinical features associated with RAOU. Finally, this study is the first to confirm H63D association with isolated RAOU.

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Why is it important?

Our findings suggest a susceptibility marker for isolated recurrent aphthous stomatitis

Perspectives

Explore the HLA class I region using microsatellite markers to refine the association study with Behçet's disease and recurrent aphthous stomatitis

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This page is a summary of: Beyond HLA Class I Antigens, HFE Mutations in Recurrent Aphthous Oral Ulcers and Behçet's Disease in The South of Tunisia, Medical Principles and Practice, September 2017, Karger Publishers,
DOI: 10.1159/000481782.
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