What is it about?
By exploring some key examples from physiology, we try to show that a holistic view of biological systems can have profound effects on our ability to draw meaningful conclusions from experiments.
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Why is it important?
The article is mainly focused on physiologists with no or little experience in systems biology. Simple concepts used to retrieve information from the biological context in which the posed question lies may help not to be misguided by simple, but inaccurate, conclusions. We also show tools that will help to design hypotheses and analyse experiments taking into consideration concepts like modularity, interolog, genetic backgrounds, etc.
Perspectives
I believe this article can be used as an introduction to several concepts in systems biology and the network field applied to biological systems. However, even an experienced researcher in those fields might profit from the several tools and databases that we suggested to the readers.
Pedro Henrique Imenez Silva
Universitat Zurich
Read the Original
This page is a summary of: Insights from Systems Biology in Physiological Studies: Learning from Context, Cellular Physiology and Biochemistry, January 2017, Karger Publishers,
DOI: 10.1159/000478648.
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