What is it about?
To investigate the effects of diet-induced obesity on the expression of nuclear factor-κB (NF-κB) and visfatin messenger RNA in male Wistar rats’ tracheae after sensitization with ovalbumin (OVA).
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Why is it important?
In this study, the expression levels of NF-κB and visfatin were markedly higher in the S+HFD group in comparison to the other groups. These findings indicate that alternative signaling pathways might be activated in diet-induced obesity associated with the OVA-sensitized animal model and could be responsible for possible altered sensitization phenotype.
Perspectives
I hope this article will help you understand the possible pathways of the relationship between asthma and obesity. Based on previous studies, asthma has been shown to be associated with obesity, but no possible mechanisms have been identified.
Dr Mohammad Reza Aslani
Ardabil University of Medical Sciencese
Read the Original
This page is a summary of: Increased Visfatin Expression is Associated with Nuclear Factor-kappa β in Obese-Ovalbumin Sensitized Male Wistar Rats Trachea, Medical Principles and Practice, April 2017, Karger Publishers,
DOI: 10.1159/000475772.
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