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The transgenic animals present a modification on the thyroid hormone receptor gene that impairs the ability to bind T3 as several patients.
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http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4797074D1&idiomaExibicao=2
Dr Tania M Ortiga-Carvalho
Federal University of Rio de Janeiro
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This page is a summary of: The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice, Cellular Physiology and Biochemistry, January 2015, Karger Publishers,
DOI: 10.1159/000430370.
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