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We proposed a new theory about development of Immunoglobulin M deficiency in a patient with carcinoma; overexpression of activation-induced cytidine deaminase (AID) may enhance the immunoglobulin class switching in B cells and carcinogenesis.

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This page is a summary of: A Novel Type of Selective Immunoglobulin M Deficiency in a Patient with Autoimmune Liver Cirrhosis with Recurrent Hepatocellular Carcinoma: A Case Report and Review of the Literature, International Archives of Allergy and Immunology, January 2013, Karger Publishers,
DOI: 10.1159/000343583.
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