What is it about?
The regional citrate anticoagulation is a safe treatment of a severe metabolic alkalosis
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Why is it important?
The case puts in doubt a widely discussed side effect of the regional citrate anticoagulation in a critically ill on a renal replacement therapy, i.e. metabolic alkalosis. This is rather caused by an inappropriate setting of the method.
Perspectives
There are few relative contraindications to the regional citrate anticoagulation and all of them may be managed by an adapted setting of the method. Thus, in accordance with the KDIGO Guidelines (Kidney Int 2012), the regional citrate anticoagulation should be offered to all critically ill with renal failure regardless of a bleeding risk.
Martin Balik
Charles University in Prague
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This page is a summary of: A Rare Case of Severe Metabolic Alkalosis with Unusual Hyperproteinemia Treated with Continuous Renal Replacement Therapy and Regional Citrate Anticoagulation, Case Reports in Nephrology and Dialysis, August 2018, Karger Publishers,
DOI: 10.1159/000491628.
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