What is it about?
Higher SLC6A4 mRNA expression in leukocytes in AD was associated with apathy regardless of SLC6A4 genotypes and methylation rates of the promoter region. The L/L genotype may reduce the risk of AD in the Caucasian population.
Photo by National Cancer Institute on Unsplash
Why is it important?
AD pathogenesis can be influenced by SLC6A4. However, the relationships among SLC6A4 polymorphisms, methylation rates, and the mRNA expression level in leukocytes in AD have not been examined.
Read the Original
This page is a summary of: Association Study and Meta-Analysis of Polymorphisms, Methylation Profiles, and Peripheral mRNA Expression of the Serotonin Transporter Gene in Patients with Alzheimer's Disease, Dementia and Geriatric Cognitive Disorders, January 2016, Karger Publishers, DOI: 10.1159/000447324.
You can read the full text:
The following have contributed to this page