What is it about?

The biomolecular mechanism for the masquerading phenomenon of DTSGCT was explained by CSF1 over-expression in the neoplastic cells attracting migration and proliferation of CSF1R positive Langerhans cells.

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Why is it important?

Diffuse type tenosynovial giant cell tumour (DTSGCT) can occur primarily in bone and mimic Langerhans cell histiocytosis.

Perspectives

Langerhans cell rich lesions may not be Langerhans cell histiocytosis

Dr Florence Cheung
Gleneagles Hospital Hong Kong

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This page is a summary of: Diffuse-Type Tenosynovial Giant Cell Tumour Involving Bone Masquerading as Langerhans Cell Histiocytosis, Case Reports in Medicine, September 2022, Hindawi Publishing Corporation,
DOI: 10.1155/2022/1992541.
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