Exosomes: A Paradigm in Drug Development against Cancer and Infectious Diseases

Mohammad Oves, Huda A. Qari, Nadeen M. Felemban, Aftab Aslam Parwaz Khan, Mohd Rehan, Shams Tabrez, Faheem Ahmed, Ashanul Haque, Mohd Shahnawaz Khan, Javed M. Khan, Fohad M. Husain, Afzal Hussain, Mohiuddin Khan Warsi, Iqbal I. M. Ismail
  • Journal of Nanomaterials, January 2018, Hindawi Publishing Corporation
  • DOI: 10.1155/2018/6895464

Exosomes: A paradigm in drug development against cancer and infectious diseases

What is it about?

Extracellular vesicles are small single lipid membrane entity secreted by eukaryotic and prokaryotic cells and play an important role in intercellular signaling and nutrient transport. The last few decades have witnessed a plethora of research on these vesicles owing to their ability to answer many hidden facts at the supramolecular level. These extracellular vesicles have attracted the researchers because they act as shuttle agents to transfer biomolecules/drugs between cells. Recently, studies have shown the application of exosomes in tumor therapy and infectious disease control. The present review article shows the importance of exosomes in cancer biology and infectious disease diagnoses and therapy and provides comprehensive account of exosomes biogenesis, extraction, molecular profiling, and application in drug delivery.

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http://dx.doi.org/10.1155/2018/6895464

The following have contributed to this page: Dr. Oves M, Ashanul Haque, and Shams Tabrez