What is it about?
Influenza A H1N1/09 pandemic, with its origin in Mexico, is the first human flu in 40 years to have caused such transmissibility and infectivity on a global scale. However, the mortality rates were merely marginal compared to those of previous global outbreaks, suggesting that susceptibility genes are involved.
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Why is it important?
No other studies were made in the Mexican population evaluating HLA genes. Our results identify by first time class I alleles associated with susceptibility to 2009 pandemic influenza A H1N1.
Perspectives
I hope this article seat the basis to future studies involving (or taking into account) genetic contribution to infectious diseases.
Dr. Ramcés Falfán-Valencia
Instituto Nacional de Enfermedades Respiratorias
Read the Original
This page is a summary of: An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study, Journal of Immunology Research, January 2018, Hindawi Publishing Corporation,
DOI: 10.1155/2018/3174868.
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