What is it about?

N-Acetylcysteine (NAC) is an amino acid. It has been used for treating many mental disorders including addiction and substance abuse, schizophrenia, obsessive-compulsive and related disorders, and depression. This article summarises the latest evidence from systematic reviews and meta-analyses to support its clinical use.

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Why is it important?

Much research was done over the past decades on its efficacy. Many systematic reviews and meta-analyses critically reviewed the available evidence. Systematic reviews are the best available evidence to support evidence-based use of a treatment in medicine. This article aims to assist the researchers, doctors, patients, and the general public to understand the available evidence on NAC better.


NAC has increasingly become a popular food supplement for alleviating the impacts of mental conditions. Unlike other psychiatric medications which have many undesirable adverse effects, NAC is safe and without any side-effects. With the supporting evidence on its efficacy to date, It should be considered as a potential treatment to curb the mental health epidemic currently affecting the whole world.

Soo Liang Ooi
Charles Sturt University

Read the Original

This page is a summary of: N-Acetylcysteine for the Treatment of Psychiatric Disorders: A Review of Current Evidence, BioMed Research International, October 2018, Hindawi Publishing Corporation,
DOI: 10.1155/2018/2469486.
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