What is it about?

This is a review of basic and clinical research on diseases caused by damage to the corneal nerve fiber and its regeneration.

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Why is it important?

The relationships between subbasal corneal nerve fiber morphology and neurotrophic keratopathy in corneal diseases are well studied. The recommended treatment for neurotrophic keratopathy is administration of preservative free eye drops.

Perspectives

Morphological observation of corneal sensory nerves using in vivo confocal microscopy will greatly contribute to the establishment of pathogenesis and treatment of diseases caused by corneal nerve damage, especially neurotrophic keratitis. However, in order for in vivo confocal microscopy to be widely used, the issue of its cost-effectiveness must be resolved.

Prof. Hiroshi Eguchi
The University of Tokushima

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This page is a summary of: Corneal Nerve Fiber Structure, Its Role in Corneal Function, and Its Changes in Corneal Diseases, BioMed Research International, January 2017, Hindawi Publishing Corporation,
DOI: 10.1155/2017/3242649.
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