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According to the results, it is concluded that bisphenol A (BPA) increased expression of HO-1 gene more than Gadd45 gene at high doses. The BPA can induce dose-dependent liver damage. Increased reactive oxygen species (ROS) and oxidative reactions may be responsible for the toxicity.

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This page is a summary of: Induction Effect of Bisphenol A on Gene Expression Involving Hepatic Oxidative Stress in Rat, Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation,
DOI: 10.1155/2016/6298515.
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