What is it about?
Fructose corn syrup is cheap sweetener and prolongs the shelf life of products, but fructose intake causes hyperinsulinemia, hypertriglyceridemia, and hypertension. All of them are referred to as metabolic syndrome and they are risk factors for cardiovascular diseases. Hence, the harmful effects of increased fructose intake on health and their prevention should take greater consideration. Caffeic Acid Phenethyl Ester (CAPE) has beneficial effects on metabolic syndrome and vascular function which is important in the prevention of cardiovascular disease. However, there are no known studies about the effect of CAPE on fructoseinduced vascular dysfunction. In this study,we examined the effect of CAPE on vascular dysfunction due to high fructose corn syrup (HFCS).
Featured Image
Why is it important?
CAPE supplements lowered HFCS consumption-induced raise in blood glucose, homocysteine, and cholesterol levels. The aorta tissue endothelial nitric oxide synthase (eNOS) production was decreased in rats given HFCS and in contrast CAPE supplementation efficiently increased its production. The presented results showed that HFCS-induced cardiovascular abnormalities could be prevented by CAPE treatment.
Perspectives
In our thesis, we think that these features of CAPE improve the metabolic syndrome symptoms occurring in the rats treated with corn syrup high fructose and the disorders occurring in the vessels. However, further studies are needed which will clarify this situation.
Dr Sedat Bilgiç
Adiyaman Universitesi
Read the Original
This page is a summary of: Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats, Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation,
DOI: 10.1155/2016/3419479.
You can read the full text:
Contributors
The following have contributed to this page
