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This is a very extensive review of published data and discussion relating to the role of pepsin in GORD and LPR. It is a must read for all those enlightened to the fact that acid is not a key factor in reflux disease pathophysiology

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This page is a summary of: Reflux Revisited: Advancing the Role of Pepsin, International Journal of Otolaryngology, January 2012, Hindawi Publishing Corporation,
DOI: 10.1155/2012/646901.
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