TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis

  • Johannes W. Dietrich, Gabi Landgrafe, Elisavet H. Fotiadou
  • Journal of Thyroid Research, January 2012, Hindawi Publishing Corporation
  • DOI: 10.1155/2012/351864

Cybernetic role of TSH in pituitary-thyroid feedback control

What is it about?

This review article on thyroid homeostasis summarizes theories of hypothalamus-pituitary-thyroid interaction. It is based on principles of systems medicine, biological cybernetics and biochemistry. Special emphasis is laid on on thyrotropin and other thyroid stimulators. In addition, it summarizes the role of calculated structure parameters like SPINA-GT, SPINA-GD or Jostel's TSH index for evaluation of thyroid function.

Why is it important?

This is the first review article that summarizes efforts in mathematical and cybernetic modelling of thyroid homeostasis.

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The following have contributed to this page: PD Dr. med. Johannes W Dietrich