What is it about?

This study was aimed at evaluating the effects of Corvitin and 2-oxoglutarate on physiological parameters, heart histology, and markers of carbonyl/oxidative stress of rats with pituitrin-isoproterenol-induced myocardial damage (PIMD).The evaluation of oxidative and carbonyl stress markers under experimental myocardial ischemia can provide additional information on the molecular mechanisms of development of CVD.

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Why is it important?

Corvitin and exogenous 2-OG show cardio- and neuroprotective effects through the decrease of carbonyl/oxidative stress and regulation of the activity of the antioxidant system.


A study of carbonyl-oxidative stress indices is important for evaluating the effectiveness of cardioprotective drugs.

Алла Shevtsova

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This page is a summary of: The Cardio- and Neuroprotective Effects of Corvitin and 2-Oxoglutarate in Rats with Pituitrin-Isoproterenol-Induced Myocardial Damage, Biochemistry Research International, September 2018, Hindawi Publishing Corporation,
DOI: 10.1155/2018/9302414.
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