What is it about?

Transfusion-transmissible infections, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and syphilis are among the greatest threats to blood safety and pose a serious public health problem.

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Why is it important?

The high prevalence of HIV, HBV, HCV, and syphilis has heightened the problems of blood safety in Ethiopia. Thus, continuous monitoring of the magnitude of transfusion-transmissible infections in blood donors is important for estimating the risk of transfusion and optimizing donor recruitment strategies to minimize infectious diseases transmission . However, there is scarce published information about the burden of major transfusion-transmissible infections in the study area. Morbidity and mortality resulting from the transfusion of infected blood have far-reaching consequences, not only for the recipients themselves, but also for their families, their communities, and the wider society . Only continuous improvement and implementation of donor selection, sensitive screening tests, and effective inactivation procedures can ensure the elimination, or at least reduction, of the risk of acquiring TTIs Evaluation of data on the prevalence of transfusion-transmissible infections, namely, HIV, HBV, HCV, and syphilis, among blood and plasma donors permits an assessment of the occurrence of infections in the blood donor population and consequently the safety of the collected donations. It also gives an idea of the prevalence of the transfusion-transmissible infections (TTIs) among blood donors which allows for assessment of epidemiology of these infections in the community


In general, the prevalence of transfusion-transmissible infection is high in the study area. The blood donors in this study were voluntary subjects, who are apparently healthy, but this study found that these diseases are prevalent among volunteer donors. Thus, strict selections of blood donors with standard methods are highly recommended to ensure the safety of blood for the recipient.

Temesgen Anjulo
Wolaita Sodo University

Read the Original

This page is a summary of: Transfusion-Transmissible Infections among Voluntary Blood Donors at Wolaita Sodo University Teaching Referral Hospital, South Ethiopia, Canadian Journal of Infectious Diseases and Medical Microbiology, January 2016, Hindawi Publishing Corporation, DOI: 10.1155/2016/8254343.
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