Induction Effect of Bisphenol A on Gene Expression Involving Hepatic Oxidative Stress in Rat

  • Sohrab Kazemi, Seydeh Narges Mousavi, Fahimeh Aghapour, Boshra Rezaee, Farzin Sadeghi, Ali Akbar Moghadamnia
  • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation
  • DOI: 10.1155/2016/6298515

What is it about?

According to the results, it is concluded that bisphenol A (BPA) increased expression of HO-1 gene more than Gadd45 gene at high doses. The BPA can induce dose-dependent liver damage. Increased reactive oxygen species (ROS) and oxidative reactions may be responsible for the toxicity.

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The following have contributed to this page: Sohrab Kazemi