What is it about?
Magic angle spinning offers an approach to study large proteins with NMR without concern as to the size of the protein.
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Why is it important?
The article outlines two new approaches that increase sensitivity and resolution in MAS spectra of proteins -- dynamic nuclear polarization (DNP) and 1H detection.
Perspectives
Together DNP and 1H detection in MAS will likely change the way we do protein NMR.
Professor Robert G. Griffin
Massachusetts Institute of Technology
Read the Original
This page is a summary of: Magic Angle Spinning NMR of Proteins: High-Frequency Dynamic Nuclear Polarization and1H Detection, Annual Review of Biochemistry, June 2015, Annual Reviews,
DOI: 10.1146/annurev-biochem-060614-034206.
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