Top-Down Proteomics Annual Review

What is it about?

Herein we explain the theory and history of top-down proteomics and the study of proteoforms, and present progress in the field especially as it pertains to high-throughput intact proteome analysis.

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Why is it important?

Top-down proteomics is becoming increasingly accessible and popular in the field, and the value of complete molecular specificity in measurement may help fulfill the promise of big omics techniques in biomarker discovery.