What is it about?

Lung cancer and its various types are a leading cause of death across the globe. Many studies have pointed out that microRNAs (miRNAs) dysregulation can be a useful marker for variety of cancers, including lung cancer. Successful treatment of all cancers depends on clinical expertise, treatment resources, and the stage at the time of diagnosis. Therefore, we made an effort to find a novel miRNA expression marker to determine the stage of lung adenocarcinoma (LUAD).

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Why is it important?

Better decision making and auxiliary for non-invasive strategies for lung cancer diagnosis and stage stratification

Perspectives

To conclude, the results obtained clearly showed the effectiveness of ensemble method for the classification of early and advanced stage LUAD using miRNA expression data. The top 10 miRNAs sequences identified by the model can help make the best treatment decisions for early and advanced stage LUAD to increase the chances of survival.

Adeel Khan
Southeast University

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This page is a summary of: Stacking Ensemble Method for Early and Advanced Stage Lung Adenocarcinoma Classification Based on miRNA Expression, October 2021, ACM (Association for Computing Machinery),
DOI: 10.1145/3498731.3498742.
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