What is it about?

The rate of DNA evolution considered is the number of nucleotide substitutions per unit of time. Estimates of the substitution rate based on mammalian DNA data agree with the lognormal distributions much better than normal distributions. That is consistent with models of molecular evolution across all times scales.

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Why is it important?

According to the proposed multiplicative evolution statistical hypothesis, fluctuations in the substitution rate result from interconnected influences, each of which has a high impact. That is very different from an additive evolution statistical hypothesis, which would instead imply that each influence on the rate has little impact in itself.

Perspectives

This paper resulted from my PhD research supervised by Bruce West. For others, follow the "Related papers" link.

David R. Bickel
University of North Carolina at Greensboro

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This page is a summary of: Multiplicative and Fractal Process in DNA Evolution, Fractals, September 1998, World Scientific Pub Co Pte Lt,
DOI: 10.1142/s0218348x98000262.
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