Propofol-balanced anaesthesia for single balloon enteroscopy: Antegrade VS Retrograde Intubation

What is it about?

Single balloon enteroscopy (SBE) procedure is a procedure for diagnosis and treatment in patients with abnormality of gastrointestinal tract especially for small bowel. It commonly performed either anterograde or retrograde intubation. The aim of the study is to compare and evaluate the success rate of propofol-balanced anaesthesia (PBA) for the SBE procedure between antegrade and retrograde intubation. The primary outcome variable of the study was the successful completion of the procedure. Failed procedure is defined as the procedure can not be completed by using PBS technique or sedation-related serious adverse events such as severe hypoxaemia (SpO2 <85% more than 3 min and can not relief by airway management), severe cardiorespiratory instability, are occurred. The secondary outcome variables were sedation-related complications, mortality rate and haemodynamic parameters.

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Why is it important?

108 patients underwent SBE procedure during the study period. After matching age, gender, weight, height, ASA physical status, duration of endoscopy and indications of procedures, there were 21 patients in group A and 19 patients in group B. There were no significant differences in age, gender, weight, height, ASA physical status, duration and indication of procedures, type of enteroscopy, anaesthetic personnel and haemodynamic parameters between the two groups. All procedures were successful completion of the endoscopies. Mean dose of propofol, fentanyl and midazolam in both groups was comparable. Overall and cardiorespiratory-related adverse events were not significantly different between the two groups. All adverse events were transient, mild degree and easier treatable. Serious adverse events were none.

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