Benefits and harms of lower blood pressure treatment targets: systematic review and meta-analysis of randomised placebo-controlled trials

What is it about?

This systematic review and meta-analysis assess benefits and harms of blood pressure lowering treatment if systolic blood pressure is between 130 and 140 mm Hg. This is important because U.S. and European gudielines recently shifted the recommended blood pressure treatment target from < 140 to < 130 mm Hg. Our findings do not support this shift, showing no treatment effect on cardiovascular outcomes but an increased risk of side effects with treatment.

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