Sclerosing angiomatoid nodular transformation of the spleen

What is it about?

Sclerosing Angiomatoid Nodular Transformation of the spleen (SANT) is a rare benign splenic growth of unknown aetiology. It is a relatively new condition that is not very well understood.

Our case report described a rare case of SANT in a middle-aged woman presented with persistent high white-cell counts, significant weight loss and upper abdominal discomfort.

In our case report, we discussed clinical features, investigations, differential diagnoses, management plan and proposed aetiology of SANT.

SANT is often asymptomatic and is usually an incidental finding on imaging. Imaging modalities like ultrasound, CT and MRI are useful in early detection of splenic masses.

Important differential diagnoses include other benign and malignant splenic growths.

It is impossible to diagnose SANT without surgical intervention and histopathology.

Surgical removal is the conventional treatment, as it is both diagnostic and therapeutic.

As SANT is still a rare and relatively new condition, more literature on this topic would guide physicians to investigate and diagnose SANT in the future.

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