Proton beam therapy for intracranial cancer

What is it about?

We report the first clinical case on the successful use of proton beam therapy in the management of malignant transformation of intracranial epidermoid cyst. A 43-year-old man was initially diagnosed as this disease with left facial paresis, hypesthesia and hypoalgesia in the territories of the trigeminal nerve. After failure of surgical interventions, he was referred to our radiation centre. We performed a post-operative proton beam therapy for treatment. We delivered a total dose of 57GyE in 31 fractions. He tolerated the treatment well with mild acute toxicities, and remained healthy and functional by 2-year follow-up post-radiotherapy. No evidence of delayed radiation-induced neurotoxicity was observed.

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Why is it important?

We report the first clinical case on the successful use of proton beam therapy in the management of malignant transformation of intracranial epidermoid cyst.