What is it about?

Pathology evaluation of Barrett’s patients’ surveillance biopsies is poorly reproducible. Guidelines mandate that biopsies with dysplasia be reviewed by an expert, but there are no evidence-based criteria to corroborate expert reviewer status. Through a large online consensus study amongst more than 50 pathologists in over 20 countries we reveal histopathologist-dependent predictors of major diagnostic error in the assessment of Barrett’s biopsies. The size of our dataset allows us to quantify the impact of these variables, such as experience commensurate with age and professional setting, in multivariate analysis.

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Why is it important?

Our data provide evidence-based criteria for diagnostic proficiency in Barrett’s histopathology and will help facilitate training and support to reduce diagnostic variability.

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This page is a summary of: Histopathologist features predictive of diagnostic concordance at expert level among a large international sample of pathologists diagnosing Barrett’s dysplasia using digital pathology, Gut, December 2019, BMJ,
DOI: 10.1136/gutjnl-2019-318985.
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