What is it about?
How motor protein Myo1c participates in regulating the trafficking of other critical podocyte proteins.
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Why is it important?
The first report that structurally defines the interaction of Myo1c with a podocyte protein Neph1.
Perspectives
Although podocytes are composed of many motor proteins but their exact function was not clear. This report provides evidence that motor proteins may participate in trafficking of the membrane proteins such as Neph1 that are critical in maintaining podocyte function and hence renal function.
Dr Deepak Nihalani
Medical University of South Carolina
Read the Original
This page is a summary of: Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1, Molecular and Cellular Biology, April 2016, ASM Journals,
DOI: 10.1128/mcb.00020-16.
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