What is it about?
Our findings show that control of Tip110/SART3 protein level may have important functional consequences on the cross-talk with key signaling pathways controlling cancer survival, which is likely to have a new impact on p53 and HIF targeting strategies for hypoxia-associated human diseases.
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Why is it important?
Our findings show that control of Tip110/SART3 protein level may have important functional consequences on the cross-talk with key signaling pathways controlling cancer survival, which is likely to have a new impact on p53 and HIF targeting strategies for hypoxia-associated human diseases.
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This page is a summary of: Tip110 Regulates the Cross Talk between p53 and Hypoxia-Inducible Factor 1α under Hypoxia and Promotes Survival of Cancer Cells, Molecular and Cellular Biology, May 2015, ASM Journals,
DOI: 10.1128/mcb.00001-15.
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