First bacterial copper importer prototype
What is it about?
Cytochrome oxidases are membrane-integral cuproproteins that catalyze oxygen reduction to water under hypoxic and normoxic growth conditions. In this study, we show that the copper atoms of the catalytic center of two similar cytochrome c oxidases from this superfamily are provided by different copper uptake systems during their production.
Why is it important?
This finding illustrates different strategies that organisms exhibit to fine-tune the trafficking of copper, which is an essential but toxic micronutrient.
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