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Why is it important?
Immunotherapy based on the use of pro-GSH molecules would permit LP-BM5 infection and probably all those viral infections characterized by GSH deficiency and aTh1/ Th2 imbalance to be more effectively combated.
Perspectives
The molecules proposed can act both as immunomodulators and antimicrobial. This means that they can combine host- and pathogen-directed treatments providing an innovative and efficient strategy to fight several pathogens.
Alessandra Fraternale
Universita degli Studi di Urbino Carlo Bo
Read the Original
This page is a summary of: Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics, Journal of Virology, May 2016, ASM Journals,
DOI: 10.1128/jvi.00603-16.
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